Dec. 16, 1960 - A TWA Constellation and a United DC-8 collided at 5,200 over Staten Island, sending the TWA aircraft down at Miller Field, while the United aircraft came to Earth in Park Slope.
In the end, 128 people and 6 on the ground were killed. One a 11-year-old boy, survived the initial crash, but died later.
That Wikipedia link has some good information that you might not find in typical articles about the tragedy. However, I'm sure with many local people and folks in the industry on this site, maybe some more knowledge can be shared about this sad day.